Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 7/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.51 |
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130335 | 0.89 | OPRD1 (0.64) | OPRK1OPRD1PARP1DRD2DRD4 | |
| SCHEMBL9128047 | 0.83 | PARP1 (0.47) | OPRK1PARP1CXCR3DRD2DRD4 | |
| SCHEMBL9130569 | 0.81 | OPRK1 (0.56) | OPRK1OPRD1 | |
| SCHEMBL9127858 | 0.80 | OPRK1 (0.53) | OPRK1OPRD1 | |
| Hydrochloric Acid SCHEMBL8788611 | 0.80 | OPRD1 (0.76) | OPRK1OPRD1 | |
| SCHEMBL9127987 | 0.78 | OPRK1 (0.53) | OPRK1OPRD1 | |
| SCHEMBL16412574 | 0.72 | PARP1 (0.50) | OPRK1OPRD1PARP1DRD2DRD4 | |
| SCHEMBL16419209 | 0.72 | PARP1 (0.50) | OPRK1OPRD1PARP1DRD2DRD4 | |
| SCHEMBL9130785 | 0.71 | PARP1 (0.46) | OPRK1PARP1CXCR3DRD2DRD4 | |
| SCHEMBL8717277 | 0.71 | ALDH1A1 (0.45) | OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472961-A | Acetamides | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-12-05 | — | — | US | disclosed |
| EP-0670318-A2 | Acetamides with analgesic and neuroprotective activity | MERCK PATENT GmbH (DE) | 1995-09-06 | — | — | EP | disclosed |