Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 2/20 | 0.36 |
| ▸ | CDC25B | P30305 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30281115 | 0.75 | LMNA (0.32) | LMNAGAAMAPTALDH1A1HTT | |
| SCHEMBL9730908 | 0.74 | — | — | |
| SCHEMBL18536620 | 0.71 | ALDH1A1 (0.43) | LMNAGAAMAPTALDH1A1HTT | |
| SCHEMBL30281067 | 0.70 | KDM4E (0.41) | LMNAGAAMAPTALDH1A1HTT | |
| SCHEMBL70825 | 0.67 | PTPN1 (0.56) | LMNAGAAMAPTALDH1A1HTT | |
| SCHEMBL5171537 | 0.67 | PTPN1 (0.45) | LMNAALDH1A1PTPN1L3MBTL1RAB9A | |
| SCHEMBL10360973 | 0.65 | PTPN1 (0.43) | LMNAGAAMAPTALDH1A1HTT | |
| SCHEMBL18957266 | 0.65 | — | — | |
| SCHEMBL8194669 | 0.65 | PTPN1 (0.59) | LMNAGAAMAPTALDH1A1HTT | |
| SCHEMBL13403500 | 0.65 | PTPN1 (0.59) | LMNAGAAMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017029397-A1 | PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL AGENT | ZAKLADY FARMACEUTYCZNE POLPHARMA SA (PL) | 2017-02-23 | — | — | WO | disclosed |
| EP-3133062-A1 | PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL AGENT | Zaklady Farmaceutyczne Polpharma SA (PL) | 2017-02-22 | — | — | EP | disclosed |
| US-5456904-A | Sunscreens; sunblocks; antiinflammatories | THE PROCTER & GAMBLE COMPANY (US) | 1995-10-10 | — | — | US | disclosed |
| WO-1995000112-A1 | PHOTOPROTECTION COMPOSITIONS COMPRISING CERTAIN CHELATING AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1995-01-05 | — | — | WO | disclosed |