Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130659 | 0.75 | LMNA (0.46) | LMNAGAAMAPTPTPN1ALDH1A1 | |
| SCHEMBL28976544 | 0.69 | LMNA (0.33) | LMNA | |
| SCHEMBL30281067 | 0.65 | KDM4E (0.41) | LMNAGAAMAPTALDH1A1HTT | |
| SCHEMBL9564568 | 0.63 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL13092048 | 0.57 | PTPN1 (0.31) | LMNAMAPTPTPN1 | |
| SCHEMBL7637933 | 0.57 | — | — | |
| SCHEMBL30281274 | 0.56 | AKT1 (0.32) | — | |
| SCHEMBL12121173 | 0.56 | — | — | |
| SCHEMBL820849 | 0.54 | LMNA (0.32) | LMNAMAPTPTPN1 | |
| SCHEMBL3744775 | 0.54 | CTSD (0.32) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |