Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12305493 | 0.80 | KMT2A (0.53) | MTNR1AMTNR1BNAPRTHSD17B10HTT | |
| SCHEMBL8505339 | 0.78 | HTT (0.54) | MTNR1AMTNR1BNAPRTHSD17B10HTT | |
| SCHEMBL5170932 | 0.78 | SMN1; SMN2 (0.46) | MTNR1AMTNR1BHTTTSHRKMT2A | |
| SCHEMBL9694716 | 0.77 | TDP1 (0.61) | HSD17B10KMT2ACYP3A4ALDH1A1TDP1 | |
| SCHEMBL20893396 | 0.77 | MTNR1A (0.46) | MTNR1AMTNR1BNAPRTHSD17B10HTT | |
| SCHEMBL10416068 | 0.77 | MTNR1A (0.46) | MTNR1AMTNR1BNAPRTHSD17B10HTT | |
| SCHEMBL14989351 | 0.77 | KMT2A (0.51) | MTNR1AMTNR1BNAPRTHSD17B10HTT | |
| SCHEMBL9545457 | 0.75 | ALDH1A1 (0.52) | MTNR1AMTNR1BNAPRTHSD17B10HTT | |
| SCHEMBL28410947 | 0.74 | NPSR1 (0.40) | NPSR1KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL6963066 | 0.74 | MTNR1A (0.43) | MTNR1AMTNR1BNAPRTHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103027906-B | The application of arctigenin in treatment anemia disease | LUNAN PHARMACEUTICAL GROUP CO., LTD. (CN) | 2015-11-11 | — | — | CN | disclosed |
| CN-104688723-A | Application of anhydroicaritin in preparation of medicine for treating anaemia | LUNAN PHARM GROUP CORP | 2015-06-10 | — | — | CN | disclosed |
| EP-0411716-B1 | Biocidal compositions | SHELL INT RESEARCH (NL) | 1995-03-22 | — | — | EP | disclosed |
| US-5387580-A | A phytopathogenic fungicides and nematocides | SHELL RESEARCH LIMITED (GB) | 1995-02-07 | — | — | US | disclosed |
| EP-0411716-A1 | Biocidal compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-02-06 | — | — | EP | disclosed |