Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9132865 | 0.85 | MAPT (0.50) | ALDH1A1PTPRCS100A4PTGS2POLB | |
| SCHEMBL376864 | 0.77 | ALDH1A1 (0.52) | HSPB1ALDH1A1PTPRCS100A4HIF1A | |
| SCHEMBL7660341 | 0.76 | ALDH1A1 (0.55) | GCGRMAPK14HSPB1ALDH1A1PTPRC | |
| SCHEMBL6201706 | 0.76 | HSPB1 (0.46) | GCGRMAPK14HSPB1ALDH1A1PTPRC | |
| SCHEMBL6201702 | 0.75 | TXNRD1 (0.53) | GCGRMAPK14HSPB1ALDH1A1PTPRC | |
| SCHEMBL27413429 | 0.74 | HTR7 (0.46) | ALDH1A1PTPRCS100A4POLBMEN1 | |
| SCHEMBL4647893 | 0.74 | ALDH1A1 (0.56) | HSPB1ALDH1A1PTPRCS100A4HIF1A | |
| SCHEMBL30648783 | 0.74 | ALDH1A1 (0.56) | HSPB1ALDH1A1PTPRCS100A4HIF1A | |
| SCHEMBL8464338 | 0.73 | PTPRC (0.52) | ALDH1A1PTPRCS100A4MEN1KMT2A | |
| SCHEMBL16013792 | 0.73 | HSD17B10 (0.55) | GCGRMAPK14HSPB1ALDH1A1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416112-A | Antiinflammatory agents | ROUSSEL UCLAF (FR) | 1995-05-16 | — | — | US | disclosed |