SCHEMBL9130886

SCHEMBL9130886

O=c1ccsn1-c1ccc(Cl)c(Cl)c1

nearest known ligand 0.73

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 12/20 0.73
PIN1 Q13526 1/20 0.73
EP300 Q09472 5/20 0.53
IDO1 P14902 2/20 0.46
RGS4 P49798 2/20 0.43
RGS8 P57771 2/20 0.43
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.41
BCL2A1 Q16548 1/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4700504 0.84 KAT2B (1.00) KAT2BPIN1EP300IDO1KMT2A
SCHEMBL7624622 0.79 KAT2B (0.64) KAT2BPIN1EP300IDO1KMT2A
SCHEMBL9132193 0.78 KAT2B (0.63) KAT2BPIN1EP300IDO1RGS4
SCHEMBL2108805 0.74 KAT2B (0.73) KAT2BPIN1RGS4RGS8KMT2A
SCHEMBL1956520 0.71 KAT2B (0.65) KAT2BPIN1EP300IDO1RGS4
SCHEMBL1953955 0.71 KAT2B (0.64) KAT2BPIN1EP300IDO1MAPT
SCHEMBL8080079 0.70 KAT2B (0.57) KAT2BPIN1RGS4RGS8KMT2A
SCHEMBL22657 0.70 KAT2B (1.00) KAT2BPIN1EP300IDO1MAPT
SCHEMBL9130618 0.69 KAT2B (0.53) KAT2BPIN1EP300IDO1KMT2A
SCHEMBL9135607 0.68 KAT2B (0.70) KAT2BPIN1EP300IDO1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5465527-A Landscaping border ABLE CORPORATION (US) 1995-11-14 US claimed
US-5465527-A Landscaping border ABLE CORPORATION (US) 1995-11-14 US disclosed
EP-0331319-B1 Method for the formation of images KONISHIROKU PHOTO IND (JP) 1994-01-26 EP disclosed
US-H1090-H High contrast; hydrazide, isothizolone, bromonitroalcohol KONICA CORPORATION (JP) 1992-08-04 US disclosed
EP-0356801-A1 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1990-03-07 EP disclosed
EP-0331319-A1 Method for the formation of images KONICA CORPORATION (JP) 1989-09-06 EP disclosed
EP-0147970-B1 MICROBIOCIDAL OR ANTIMICROBIAL BIOMEDICAL DEVICES ROHM AND HAAS COMPANY (US) 1989-03-01 EP disclosed
EP-0090584-B1 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1986-12-03 EP disclosed
US-4542169-A Biomedical devices containing isothiazolones to control bacteria growth ROHM AND HAAS COMPANY (US) 1985-09-17 US disclosed
EP-0147970-A1 Microbiocidal or antimicrobial biomedical devices ROHM AND HAAS COMPANY (US) 1985-07-10 EP disclosed
US-4325201-A BACTERICIDES, FUNGICIDES, PESTICIDES, AND SLIMICIDES; PAINTS; PRESERVATIVES ROHM AND HAAS COMPANY (US) 1982-04-20 US disclosed
US-4322475-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1982-03-30 US disclosed
US-4279762-A Cutting oils containing 3-isothiazolones as biocides ROHM AND HAAS COMPANY (US) 1981-07-21 US disclosed
US-4265899-A FUNGICIDES, BACTERICIDES ROHM AND HAAS COMPANY (US) 1981-05-05 US disclosed
US-4252694-A MICROBIOCIDES ROHM AND HAAS COMPANY (US) 1981-02-24 US disclosed
US-4243403-A BACTERICIDES, ACRYLIC POLYMERS, FUNGICIDES ROHM AND HAAS COMPANY (US) 1981-01-06 US disclosed
US-4241214-A BACTERICIDE, FUNGICIDE AND ALGAECIDE ROHM AND HAAS COMPANY (US) 1980-12-23 US disclosed
US-4150026-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1979-04-17 US disclosed
US-4105431-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1978-08-08 US disclosed
US-4062946-A 3-ISOTHIAZOLONES ROHM AND HAAS COMPANY (US) 1977-12-13 US disclosed