SCHEMBL7624622

SCHEMBL7624622

O=c1ccsn1-c1ccc(Cl)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 11/20 0.64
EP300 Q09472 6/20 0.64
PIN1 Q13526 1/20 0.64
IDO1 P14902 2/20 0.49
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
MC4R P32245 1/20 0.46
OPRK1 P41145 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
GPR35 Q9HC97 1/20 0.46
PMM2 O15305 1/20 0.43
G6PD P11413 1/20 0.43
MPI P34949 1/20 0.43
CREBBP Q92793 1/20 0.42
KAT2A Q92830 1/20 0.42
MGLL Q99685 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1956520 0.79 KAT2B (0.65) KAT2BEP300PIN1IDO1ALDH1A1
SCHEMBL9132193 0.79 KAT2B (0.63) KAT2BEP300PIN1IDO1MEN1
SCHEMBL9130886 0.79 KAT2B (0.73) KAT2BEP300PIN1IDO1MEN1
SCHEMBL4700504 0.78 KAT2B (1.00) KAT2BEP300PIN1IDO1MEN1
SCHEMBL1955099 0.75 KAT2B (0.58) KAT2BEP300PIN1IDO1ALDH1A1
SCHEMBL9130618 0.73 KAT2B (0.53) KAT2BEP300PIN1IDO1MEN1
SCHEMBL465814 0.71 KAT2B (0.53) KAT2BEP300PIN1IDO1MEN1
SCHEMBL7623894 0.69 KAT2B (0.67) KAT2BEP300MEN1ALDH1A1MAPT
SCHEMBL2808252 0.68 ALDH1A1 (0.70) KAT2BEP300PIN1MEN1ALDH1A1
SCHEMBL9515005 0.67 KAT2B (0.68) KAT2BEP300MEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020128311-A1 Halocyanoacetamide antimicrobial compositions GIRONDA KEVIN F (US) 2002-09-12 US claimed
CN-1362018-A Halocyanoacetamide antimicrobial composition ROHM & HAAS (US) 2002-08-07 CN claimed
US-5465527-A Landscaping border ABLE CORPORATION (US) 1995-11-14 US claimed
CN-1303882-C Halocyanoacetamide antimicrobial composition ROHM & HAAS (US) 2007-03-14 CN disclosed
US-20020128311-A1 Halocyanoacetamide antimicrobial compositions GIRONDA KEVIN F (US) 2002-09-12 US disclosed
CN-1362018-A Halocyanoacetamide antimicrobial composition ROHM & HAAS (US) 2002-08-07 CN disclosed
EP-1219172-A1 Halocyanoacetamide antimicrobial compositions ROHM AND HAAS COMPANY (US) 2002-07-03 EP disclosed
US-5465527-A Landscaping border ABLE CORPORATION (US) 1995-11-14 US disclosed
EP-0147970-B1 MICROBIOCIDAL OR ANTIMICROBIAL BIOMEDICAL DEVICES ROHM AND HAAS COMPANY (US) 1989-03-01 EP disclosed
US-4542169-A Biomedical devices containing isothiazolones to control bacteria growth ROHM AND HAAS COMPANY (US) 1985-09-17 US disclosed
EP-0147970-A1 Microbiocidal or antimicrobial biomedical devices ROHM AND HAAS COMPANY (US) 1985-07-10 EP disclosed
US-4322475-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1982-03-30 US disclosed
US-4279762-A Cutting oils containing 3-isothiazolones as biocides ROHM AND HAAS COMPANY (US) 1981-07-21 US disclosed
US-4265899-A FUNGICIDES, BACTERICIDES ROHM AND HAAS COMPANY (US) 1981-05-05 US disclosed
US-4252694-A MICROBIOCIDES ROHM AND HAAS COMPANY (US) 1981-02-24 US disclosed
US-4243403-A BACTERICIDES, ACRYLIC POLYMERS, FUNGICIDES ROHM AND HAAS COMPANY (US) 1981-01-06 US disclosed
US-4241214-A BACTERICIDE, FUNGICIDE AND ALGAECIDE ROHM AND HAAS COMPANY (US) 1980-12-23 US disclosed
US-4150026-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1979-04-17 US disclosed
US-4105431-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1978-08-08 US disclosed
US-4062946-A 3-ISOTHIAZOLONES ROHM AND HAAS COMPANY (US) 1977-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128311-A1 Halocyanoacetamide antimicrobial compositions HDHD5, DGKI, DAGLA KAT2B 1127/4885EP300 218/4885PIN1 672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.