Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 10/20 | 0.64 |
| ▸ | EP300 | Q09472 | 5/20 | 0.64 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | G6PD | P11413 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22657 | 0.78 | KAT2B (1.00) | KAT2BEP300PIN1IDO1ALDH1A1 | |
| SCHEMBL20718809 | 0.62 | — | — | |
| SCHEMBL2539751 | 0.60 | F10 (0.39) | ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL10668708 | 0.59 | MGLL (0.75) | ALDH1A1PKMTDP1HSP90AA1 | |
| SCHEMBL147275 | 0.58 | — | — | |
| SCHEMBL325211 | 0.55 | KMT2A (0.64) | ALDH1A1HTT | |
| SCHEMBL11283275 | 0.54 | ALDH1A1 (0.53) | KAT2BEP300IDO1ALDH1A1G6PD | |
| Calcium Chloride SCHEMBL21625034 | 0.54 | INMT (0.45) | KAT2BEP300PIN1IDO1ALDH1A1 | |
| SCHEMBL22006173 | 0.54 | — | — | |
| SCHEMBL3858961 | 0.53 | EIF2AK2 (0.39) | ALDH1A1HSD17B10CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518957-B2 | Methanocarba adenosine derivatives, pharmaceutical compositions, and method of reducing intraocular pressure | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-08-27 | — | — | US | disclosed |
| US-20120264769-A1 | METHANOCARBA ADENOSINE DERIVATIVES AND DENDRIMER CONJUGATES THEREOF | The United States of Americia, as represented by the Secretary, Department of Health and Human Serv (US) | 2012-10-18 | — | — | US | disclosed |
| EP-2507241-A1 | METHANOCARBA ADENOSINE DERIVATIVES AND DENDRIMER CONJUGATES THEREOF | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011068978-A1 | METHANOCARBA ADENOSINE DERIVATIVES AND DENDRIMER CONJUGATES THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2011-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264769-A1 | METHANOCARBA ADENOSINE DERIVATIVES AND DENDRIMER CONJUGATES THEREOF | ADORA3, ADORA2A, ADORA1 | KAT2B 4655/4885EP300 4729/4885PIN1 4540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.