SCHEMBL9130618

SCHEMBL9130618

O=c1ccsn1-c1ccc(Cl)cc1Cl

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 9/20 0.53
PIN1 Q13526 1/20 0.53
IDO1 P14902 1/20 0.53
G6PD P11413 1/20 0.49
MPI P34949 1/20 0.46
PHOSPHO1 Q8TCT1 1/20 0.46
EP300 Q09472 4/20 0.43
TLR8 Q9NR97 1/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
ALOX12 P18054 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 1/20 0.38
BCL2A1 Q16548 1/20 0.38
KDM4E B2RXH2 1/20 0.37
HTT P42858 1/20 0.37
HCAR1 Q9BXC0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9134022 0.86 KAT2B (0.53) KAT2BPIN1IDO1G6PDMPI
SCHEMBL9135607 0.78 KAT2B (0.70) KAT2BPIN1IDO1G6PDEP300
SCHEMBL7624622 0.73 KAT2B (0.64) KAT2BPIN1IDO1G6PDMPI
SCHEMBL9132193 0.73 KAT2B (0.63) KAT2BPIN1IDO1G6PDMPI
SCHEMBL9132177 0.71 KAT2B (0.71) KAT2BPIN1IDO1G6PDPHOSPHO1
SCHEMBL9130886 0.69 KAT2B (0.73) KAT2BPIN1IDO1EP300MEN1
SCHEMBL13886603 0.69 KAT2B (1.00) KAT2BPIN1IDO1G6PDMPI
SCHEMBL4700504 0.69 KAT2B (1.00) KAT2BPIN1IDO1MPIPHOSPHO1
SCHEMBL9132029 0.68 ALDH1A1 (0.51) IDO1G6PDMEN1MAPTKMT2A
SCHEMBL8373511 0.66 G6PD (1.00) G6PDMPIPHOSPHO1MAPTALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5465527-A Landscaping border ABLE CORPORATION (US) 1995-11-14 US claimed
US-5465527-A Landscaping border ABLE CORPORATION (US) 1995-11-14 US disclosed
EP-0147970-B1 MICROBIOCIDAL OR ANTIMICROBIAL BIOMEDICAL DEVICES ROHM AND HAAS COMPANY (US) 1989-03-01 EP disclosed
US-4542169-A Biomedical devices containing isothiazolones to control bacteria growth ROHM AND HAAS COMPANY (US) 1985-09-17 US disclosed
EP-0147970-A1 Microbiocidal or antimicrobial biomedical devices ROHM AND HAAS COMPANY (US) 1985-07-10 EP disclosed
US-4396413-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1983-08-02 US disclosed
US-4325201-A BACTERICIDES, FUNGICIDES, PESTICIDES, AND SLIMICIDES; PAINTS; PRESERVATIVES ROHM AND HAAS COMPANY (US) 1982-04-20 US disclosed
US-4322475-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1982-03-30 US disclosed
US-4279762-A Cutting oils containing 3-isothiazolones as biocides ROHM AND HAAS COMPANY (US) 1981-07-21 US disclosed
US-4265899-A FUNGICIDES, BACTERICIDES ROHM AND HAAS COMPANY (US) 1981-05-05 US disclosed
US-4252694-A MICROBIOCIDES ROHM AND HAAS COMPANY (US) 1981-02-24 US disclosed
US-4243403-A BACTERICIDES, ACRYLIC POLYMERS, FUNGICIDES ROHM AND HAAS COMPANY (US) 1981-01-06 US disclosed
US-4241214-A BACTERICIDE, FUNGICIDE AND ALGAECIDE ROHM AND HAAS COMPANY (US) 1980-12-23 US disclosed
US-4150026-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1979-04-17 US disclosed
US-4105431-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1978-08-08 US disclosed
US-4062946-A 3-ISOTHIAZOLONES ROHM AND HAAS COMPANY (US) 1977-12-13 US disclosed