Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9132013 | 1.00 | NFKB1 (0.50) | NFKB1CA1CA2CA4TRIM24 | |
| SCHEMBL7607193 | 0.79 | NFKB1 (0.53) | NFKB1CA1CA2CA4TRIM24 | |
| SCHEMBL4452379 | 0.79 | CA2 (0.53) | NFKB1CA1CA2CA4TRIM24 | |
| SCHEMBL1137305 | 0.76 | AKR1C3 (0.59) | NFKB1CA1CA2CA4TRIM24 | |
| SCHEMBL7067852 | 0.76 | CA2 (0.50) | NFKB1CA1CA2CA4TRIM24 | |
| SCHEMBL208434 | 0.76 | AKR1C3 (0.59) | NFKB1CA1CA2CA4TRIM24 | |
| SCHEMBL7067854 | 0.76 | CA2 (0.50) | NFKB1CA1CA2CA4TRIM24 | |
| SCHEMBL7436213 | 0.76 | KDM4E (0.55) | MAPT | |
| SCHEMBL7827946 | 0.76 | NFKB1 (0.46) | NFKB1CA1CA2CA4TRIM24 | |
| SCHEMBL7436220 | 0.76 | KDM4E (0.55) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5421897-A | Applying liquid composition to surface contaminated with lead, solidifying into matrix which sequesters lead, removing matrix | GRAWE JOHN (US) | 1995-06-06 | — | — | US | claimed |
| US-5421897-A | Applying liquid composition to surface contaminated with lead, solidifying into matrix which sequesters lead, removing matrix | GRAWE JOHN (US) | 1995-06-06 | — | — | US | disclosed |