Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | TSHR | P16473 | 6/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10550459 | 0.85 | ALDH1A1 (0.60) | TDP1NPSR1TP53HTTKDM4E | |
| SCHEMBL27953738 | 0.84 | KMT2A (0.63) | TDP1NPSR1HTTKDM4EHSD17B10 | |
| SCHEMBL10549512 | 0.84 | KDM4E (0.49) | TDP1NPSR1TP53HTTKDM4E | |
| SCHEMBL10552133 | 0.83 | KDM4E (0.44) | TDP1NPSR1TP53HTTKDM4E | |
| SCHEMBL10552718 | 0.82 | KDM4E (0.49) | TDP1NPSR1TP53HTTKDM4E | |
| SCHEMBL10552129 | 0.82 | LMNA (0.44) | TDP1NPSR1TP53HTTKDM4E | |
| SCHEMBL14855833 | 0.82 | TSHR (0.67) | TDP1NPSR1TP53HTTKDM4E | |
| SCHEMBL7312805 | 0.81 | LMNA (0.71) | TDP1NPSR1TP53HTTKDM4E | |
| SCHEMBL2860044 | 0.81 | KDM4E (0.68) | TDP1NPSR1TP53HTTKDM4E | |
| SCHEMBL31126834 | 0.81 | KDM4E (0.68) | TDP1NPSR1TP53HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104557691-A | 3-aminoacyl bishydrazide derivatives, and preparation method and application thereof | UNIV CHINA AGRICULTURAL | 2015-04-29 | — | — | CN | disclosed |
| US-5475106-A | Agonist for cholecystokinin and gastrin receptors; nervous system, gastrointestinal disorders | RHONE-POULENC RORER S.A. (FR) | 1995-12-12 | — | — | US | disclosed |