Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10549512 | 0.88 | KDM4E (0.49) | ALDH1A1TSHRKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL10552718 | 0.87 | KDM4E (0.49) | ALDH1A1TSHRKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9133220 | 0.85 | TDP1 (0.63) | ALDH1A1TSHRKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL27953738 | 0.81 | KMT2A (0.63) | ALDH1A1TSHRKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL1532488 | 0.80 | ALDH1A1 (0.72) | ALDH1A1TSHRADRA1DADRA1AADRA1B | |
| SCHEMBL10552133 | 0.80 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL10552129 | 0.78 | LMNA (0.44) | ALDH1A1TSHRKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL13676821 | 0.78 | KDM4E (0.48) | ALDH1A1TSHRKDM4EMAPK1LMNA | |
| SCHEMBL4156818 | 0.77 | PDK1 (0.51) | TSHRADRA1AADRA1BKDM4EHSD17B10 | |
| SCHEMBL42787 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TSHRADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847202-A | Heterocyclic inhibitors of serine proteases | GEORGIA TECH RESEARCH INSTITUTE (US) | 1989-07-11 | — | — | US | disclosed |
| US-4585793-A | Thioester inhibitors of serine proteases | GEORGIA TECH RESEARCH INSTITUTE (US) | 1986-04-29 | — | — | US | disclosed |