Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135517 | 0.81 | MAPT (0.37) | PTPRCALDH1A1 | |
| SCHEMBL9135364 | 0.79 | CTNNB1 (0.38) | POLBLMNACTNNB1WNT3AKDM4E | |
| SCHEMBL3121726 | 0.73 | ACP1 (0.39) | POLBLMNAPTPRCPTGESPSEN1 | |
| SCHEMBL18740444 | 0.71 | ALDH1A1 (0.46) | POLBLMNAPTGESPSEN1PSEN2 | |
| SCHEMBL1433121 | 0.71 | EPHX2 (0.43) | POLBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9779474 | 0.71 | GAA (0.40) | POLBLMNAPTPRCKDM4EALDH1A1 | |
| SCHEMBL1433633 | 0.71 | IDH1 (0.47) | POLBLMNAPSEN1PSEN2APH1B | |
| SCHEMBL1433412 | 0.70 | RAPGEF3 (0.46) | POLBLMNAPTGESPSEN1PSEN2 | |
| SCHEMBL1688815 | 0.70 | POLB (0.47) | POLBLMNAPTPRCCTNNB1KDM4E | |
| SCHEMBL25185645 | 0.68 | CTSS (0.38) | POLBPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475106-A | Agonist for cholecystokinin and gastrin receptors; nervous system, gastrointestinal disorders | RHONE-POULENC RORER S.A. (FR) | 1995-12-12 | — | — | US | disclosed |