Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4993142 | 0.78 | PTPN2 (0.36) | POLBKMT2ATDP1NPC1TP53 | |
| SCHEMBL9135517 | 0.77 | MAPT (0.37) | GSK3BNPC1TP53MAPTHPGD | |
| SCHEMBL5049650 | 0.76 | PKM (0.45) | GSK3BPOLBKMT2AKDM4ENPC1 | |
| SCHEMBL11498343 | 0.75 | PTK2 (0.56) | KMT2AKDM4ENPC1TP53MAPT | |
| SCHEMBL15165515 | 0.74 | — | — | |
| SCHEMBL9135364 | 0.74 | CTNNB1 (0.38) | POLBKDM4EMAPK8PTPN2PTPRB | |
| SCHEMBL6857304 | 0.72 | PTPN2 (0.48) | GSK3BPOLBKMT2AKDM4ENPC1 | |
| SCHEMBL27780906 | 0.72 | KDM4E (0.42) | POLBKMT2AKDM4ENPC1HPGD | |
| Hydrochloric Acid SCHEMBL6775496 | 0.71 | ALDH1A1 (0.38) | GSK3BKMT2AKDM4ENPC1RAB9A | |
| SCHEMBL12213152 | 0.71 | PTK2 (0.59) | GSK3BPOLBTDP1NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475106-A | Agonist for cholecystokinin and gastrin receptors; nervous system, gastrointestinal disorders | RHONE-POULENC RORER S.A. (FR) | 1995-12-12 | — | — | US | disclosed |