Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | RAD52 | P43351 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156680 | 0.87 | ALDH1A1 (0.47) | LMNATP53CA12CA9KMT2A | |
| SCHEMBL8860030 | 0.87 | CA12 (0.60) | CA12CA9KMT2AALDH1A1NPC1 | |
| SCHEMBL9135198 | 0.85 | CA12 (0.49) | TP53CA12CA9KMT2AALDH1A1 | |
| SCHEMBL9135623 | 0.85 | CA12 (0.46) | CA12CA9KMT2AALDH1A1NPC1 | |
| SCHEMBL8828063 | 0.85 | RAB9A (0.49) | CA12CA9KMT2AALDH1A1NPC1 | |
| SCHEMBL9159771 | 0.84 | CA12 (0.57) | CA12CA9KMT2AALDH1A1NPC1 | |
| SCHEMBL9135784 | 0.84 | LMNA (0.47) | LMNATP53KMT2AALDH1A1NPC1 | |
| SCHEMBL9134700 | 0.84 | LMNA (0.52) | LMNATP53CA12CA9KMT2A | |
| SCHEMBL9134378 | 0.82 | CYP1A2 (0.48) | CA12CA9KMT2AALDH1A1NPC1 | |
| SCHEMBL9152136 | 0.82 | BCHE (0.54) | KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475106-A | Agonist for cholecystokinin and gastrin receptors; nervous system, gastrointestinal disorders | RHONE-POULENC RORER S.A. (FR) | 1995-12-12 | — | — | US | disclosed |