Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157966 | 0.89 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL9157740 | 0.89 | KMT2A (0.66) | KMT2AMEN1CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL9131858 | 0.83 | BCHE (0.75) | BCHECES1KMT2AMEN1CYP1A2 | |
| SCHEMBL9135833 | 0.82 | LMNA (0.49) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL9158437 | 0.81 | HPGD (0.53) | KMT2AMEN1ALDH1A1THRB | |
| SCHEMBL9153787 | 0.81 | KMT2A (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9156680 | 0.81 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL9159221 | 0.81 | MEN1 (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9153770 | 0.81 | SMN1; SMN2 (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9157115 | 0.78 | MEN1 (0.50) | KMT2AMEN1SMN1; SMN2THRBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |