Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135278 | 0.88 | AGTR1 (0.34) | AGTR1ALDH1A1LMNA | |
| SCHEMBL8912878 | 0.78 | LMNA (0.40) | AGTR1ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL9136773 | 0.77 | ALDH1A1 (0.37) | AGTR1ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL9136007 | 0.76 | AGTR1 (0.46) | AGTR1 | |
| SCHEMBL9309617 | 0.74 | MAPT (0.34) | AGTR1ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL9135115 | 0.74 | AGTR1 (0.37) | AGTR1 | |
| SCHEMBL2161550 | 0.73 | ABCG2 (0.41) | AGTR1ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL8913418 | 0.72 | ALDH1A1 (0.37) | AGTR1ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL9311085 | 0.72 | FGFR1 (0.38) | AGTR1ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL9311096 | 0.72 | AGTR1 (0.33) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387684-A | For treatment and prophylaxis of angiotensin II-mediated diseases such as circulatory diseases of hypertension and heart failure | THE GREEN CROSS CORPORATION (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0602246-A1 | ISOINDAZOLE COMPOUND | THE GREEN CROSS CORPORATION (JP) | 1994-06-22 | — | — | EP | disclosed |