Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957667 | 0.89 | HSD17B1 (0.50) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL3680161 | 0.84 | HSD17B1 (0.61) | ALDH1A1CA12CA2CA9CA14 | |
| SCHEMBL5685565 | 0.83 | CA12 (0.56) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL17051267 | 0.82 | HSD17B1 (0.58) | ALDH1A1CA12CA2CA9CA14 | |
| SCHEMBL4779452 | 0.82 | HSD17B1 (0.64) | ALDH1A1CA12CA2CA9CA14 | |
| SCHEMBL2989031 | 0.81 | MAOA (0.57) | ALDH1A1TDP1CDK5CDK5R1PTPRC | |
| SCHEMBL6011365 | 0.81 | CA12 (0.54) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL6573001 | 0.81 | CA12 (0.54) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL1099351 | 0.81 | MAOA (0.57) | ALDH1A1TDP1CDK5CDK5R1PTPRC | |
| SCHEMBL11601339 | 0.81 | ALOX5 (0.59) | ALDH1A1CDK5CDK5R1HPGDHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288836-A | Low temperature interfacial polymerization; photreceptor materials | XEROX CORPORATION (US) | 1994-02-22 | — | — | US | claimed |
| US-5419992-A | Photoconductive imaging member | XEROX CORPORATION (US) | 1995-05-30 | — | — | US | disclosed |
| US-5288836-A | Low temperature interfacial polymerization; photreceptor materials | XEROX CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |