Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9137989 | 0.93 | GPR4 (0.50) | GPR4 | |
| Water SCHEMBL9138362 | 0.86 | — | — | |
| SCHEMBL9569267 | 0.85 | — | — | |
| SCHEMBL9135706 | 0.82 | — | — | |
| SCHEMBL9137156 | 0.82 | GPR4 (0.53) | GPR4 | |
| SCHEMBL13743046 | 0.79 | AGTR1 (0.66) | — | |
| SCHEMBL9563125 | 0.79 | AGTR1 (0.57) | GPR4 | |
| SCHEMBL14409680 | 0.76 | — | — | |
| SCHEMBL8999099 | 0.76 | — | — | |
| SCHEMBL9140028 | 0.75 | PPARG (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459147-A | Angeotensin-antagonistic effects; hypotensive, antiischemic, and antidiabetic agents, treating glaucoma | DR. KARL THOMAE GMBH (DE) | 1995-10-17 | — | — | US | disclosed |
| EP-0560330-A2 | Substituted benzimidazolyl derivatives, therapeutic agents containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-09-15 | — | — | EP | disclosed |