Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 3/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139089 | 0.93 | GPR4 (0.51) | GPR4AGTR1AGTR2 | |
| SCHEMBL9563137 | 0.82 | AGTR2 (0.57) | GPR4AGTR1AGTR2 | |
| SCHEMBL9136697 | 0.82 | GPR4 (0.52) | GPR4 | |
| SCHEMBL9569267 | 0.82 | — | — | |
| Water SCHEMBL9138362 | 0.81 | — | — | |
| SCHEMBL8140704 | 0.79 | GPR4 (0.54) | GPR4AGTR1AGTR2 | |
| SCHEMBL9135706 | 0.79 | — | — | |
| SCHEMBL8741166 | 0.78 | AGTR2 (0.61) | GPR4AGTR1AGTR2 | |
| SCHEMBL8999434 | 0.78 | — | — | |
| SCHEMBL9135348 | 0.77 | PPARG (0.58) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459147-A | Angeotensin-antagonistic effects; hypotensive, antiischemic, and antidiabetic agents, treating glaucoma | DR. KARL THOMAE GMBH (DE) | 1995-10-17 | — | — | US | disclosed |
| EP-0560330-A2 | Substituted benzimidazolyl derivatives, therapeutic agents containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-09-15 | — | — | EP | disclosed |