Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 11/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 11/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9141906 | 1.00 | KCNE1 (0.34) | KCNE1KCNQ1TDP1NPSR1IDO1 | |
| SCHEMBL9143370 | 0.79 | NPSR1 (0.37) | KCNE1KCNQ1TDP1NPSR1IDO1 | |
| SCHEMBL9141433 | 0.74 | ABCC9 (0.39) | KCNE1KCNQ1ABCC9CYP1A2CYP2D6 | |
| SCHEMBL9141437 | 0.74 | ABCC9 (0.39) | KCNE1KCNQ1ABCC9CYP1A2CYP2D6 | |
| SCHEMBL9581848 | 0.73 | KCNA5 (0.39) | KCNE1KCNQ1IDO1MEN1CYP1A2 | |
| SCHEMBL9581830 | 0.73 | KCNA5 (0.39) | KCNE1KCNQ1IDO1MEN1CYP1A2 | |
| SCHEMBL9146935 | 0.71 | IDO1 (0.39) | KCNE1KCNQ1IDO1ABCC9L3MBTL1 | |
| SCHEMBL9197778 | 0.71 | IDO1 (0.39) | KCNE1KCNQ1IDO1ABCC9L3MBTL1 | |
| SCHEMBL11613059 | 0.71 | ABCC9 (0.42) | TDP1IDO1ABCC9MEN1CYP3A4 | |
| SCHEMBL11613063 | 0.71 | ABCC9 (0.42) | TDP1IDO1ABCC9MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391751-A | Hypotensive, antiarrhythmia, antiasthmatic agents | RED BALLOON INVESTMENT LIMITED (JE) | 1995-02-21 | — | — | US | disclosed |
| US-5284838-A | Hypotensive agents | ELF SANOFI (FR) | 1994-02-08 | — | — | US | disclosed |