Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 8/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 8/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9141908 | 0.79 | KCNE1 (0.34) | NPSR1TDP1HTR2AHTR2BABCC9 | |
| SCHEMBL9141906 | 0.79 | KCNE1 (0.34) | NPSR1TDP1HTR2AHTR2BABCC9 | |
| SCHEMBL8902117 | 0.76 | ABCC9 (0.41) | ABCC9IDO1KCNE1KCNQ1ABCB1 | |
| SCHEMBL9141437 | 0.73 | ABCC9 (0.39) | ABCC9KCNE1KCNQ1ABCB1 | |
| SCHEMBL9141433 | 0.73 | ABCC9 (0.39) | ABCC9KCNE1KCNQ1ABCB1 | |
| SCHEMBL9359331 | 0.73 | KCNA5 (0.38) | IDO1KCNE1KCNQ1ABCB1 | |
| SCHEMBL7768140 | 0.70 | ABCC9 (0.39) | TDP1ABCC9IDO1MEN1KMT2A | |
| SCHEMBL3942509 | 0.70 | ABCC9 (0.39) | TDP1ABCC9IDO1MEN1KMT2A | |
| SCHEMBL14765559 | 0.70 | ABCC9 (0.39) | TDP1ABCC9IDO1MEN1KMT2A | |
| SCHEMBL3947212 | 0.70 | ABCC9 (0.39) | TDP1ABCC9IDO1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391751-A | Hypotensive, antiarrhythmia, antiasthmatic agents | RED BALLOON INVESTMENT LIMITED (JE) | 1995-02-21 | — | — | US | disclosed |
| US-5284838-A | Hypotensive agents | ELF SANOFI (FR) | 1994-02-08 | — | — | US | disclosed |