Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | CAD | P27708 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9142172 | 1.00 | PPID (0.48) | PPIDL3MBTL1TAS1R3TAS1R1KMT2A | |
| SCHEMBL13430545 | 0.87 | TAS1R3 (0.43) | TAS1R3TAS1R1KMT2APOLBBIRC2 | |
| SCHEMBL21777305 | 0.86 | PPID (0.48) | PPIDL3MBTL1TAS1R3TAS1R1KMT2A | |
| SCHEMBL21792020 | 0.86 | PPID (0.48) | PPIDL3MBTL1TAS1R3TAS1R1KMT2A | |
| SCHEMBL14902193 | 0.84 | L3MBTL1 (0.50) | PPIDL3MBTL1TAS1R3TAS1R1KMT2A | |
| SCHEMBL3861349 | 0.84 | PPID (0.50) | PPIDL3MBTL1TAS1R3TAS1R1KMT2A | |
| SCHEMBL3861350 | 0.84 | PPID (0.50) | PPIDL3MBTL1TAS1R3TAS1R1KMT2A | |
| SCHEMBL21261621 | 0.83 | PPID (0.46) | PPIDL3MBTL1TAS1R3TAS1R1KMT2A | |
| SCHEMBL6900424 | 0.81 | PPID (0.50) | PPIDL3MBTL1TAS1R3TAS1R1BIRC2 | |
| SCHEMBL5813379 | 0.81 | ALDH1A1 (0.60) | PPIDL3MBTL1TAS1R3TAS1R1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466801-A | Process for the preparation of 3-, 6-substituted 2,5-morpholinediones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-11-14 | — | — | US | disclosed |
| WO-1994003441-A1 | PROCESS FOR THE PREPARATION OF 3-, 6-SUBSTITUTED 2,5-MORPHOLINEDIONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-02-17 | — | — | WO | disclosed |