Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 12/20 | 0.48 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269364 | 1.00 | ABCC9 (0.48) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9143634 | 1.00 | ABCC9 (0.48) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL8203937 | 0.87 | ABCC9 (0.38) | ABCC9LMNAALPLHIF1A | |
| SCHEMBL8084937 | 0.86 | ABCC9 (0.50) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9451127 | 0.86 | ABCC9 (0.44) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL10696682 | 0.86 | ABCC9 (0.48) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9736167 | 0.86 | ABCC9 (0.37) | ABCC9LMNAALPLHIF1A | |
| SCHEMBL8084431 | 0.85 | ALDH1A1 (0.39) | ABCC9CYP2C9CYP2C19LMNAALPL | |
| SCHEMBL9451150 | 0.85 | ABCC9 (0.44) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL8135770 | 0.85 | ALPL (0.36) | ABCC9ALPLHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391751-A | Hypotensive, antiarrhythmia, antiasthmatic agents | RED BALLOON INVESTMENT LIMITED (JE) | 1995-02-21 | — | — | US | disclosed |