Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | TLR3 | O15455 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269364 | 0.86 | ABCC9 (0.48) | ABCC9HIF1ALMNAALPL | |
| SCHEMBL9143634 | 0.86 | ABCC9 (0.48) | ABCC9HIF1ALMNAALPL | |
| SCHEMBL9143643 | 0.86 | ABCC9 (0.48) | ABCC9HIF1ALMNAALPL | |
| SCHEMBL9736968 | 0.85 | IDO1 (0.38) | ABCC9SMN1; SMN2ALDH1A1 | |
| SCHEMBL9735412 | 0.85 | ABCC9 (0.32) | ABCC9DRD2HTR2ALMNA | |
| SCHEMBL9735244 | 0.84 | LMNA (0.36) | ABCC9LMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8203937 | 0.84 | ABCC9 (0.38) | ABCC9HIF1ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL9738250 | 0.82 | OPRM1 (0.36) | ABCC9DRD2MAPTSMN1; SMN2 | |
| SCHEMBL9734831 | 0.82 | ALOX5 (0.37) | ABCC9SMN1; SMN2ALDH1A1 | |
| SCHEMBL8536595 | 0.82 | ABCC9 (0.49) | ABCC9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0415065-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |