Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.45 |
| ▸ | HTR1A | P08908 | 9/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9179397 | 0.83 | SIGMAR1 (0.55) | SIGMAR1HTR1AGRIN2BDRD2DRD3 | |
| SCHEMBL9178363 | 0.75 | SIGMAR1 (0.41) | SIGMAR1HTR1AGRIN2BDRD2DRD3 | |
| SCHEMBL9174172 | 0.75 | SIGMAR1 (0.43) | SIGMAR1HTR1AGRIN2BHTR6 | |
| SCHEMBL9175467 | 0.74 | SIGMAR1 (0.40) | SIGMAR1HTR1AGRIN2BTMEM97 | |
| SCHEMBL8304636 | 0.72 | OPRM1 (0.41) | HTR1ADRD2DRD3 | |
| SCHEMBL2688223 | 0.72 | GRIN2B (0.55) | SIGMAR1HTR1AGRIN2B | |
| SCHEMBL8306497 | 0.71 | SIGMAR1 (0.42) | SIGMAR1HTR1ATMEM97 | |
| SCHEMBL8303444 | 0.70 | SIGMAR1 (0.55) | SIGMAR1DRD2 | |
| SCHEMBL8303871 | 0.69 | OPRM1 (0.42) | SIGMAR1HTR1ADRD2ACHE | |
| SCHEMBL1038534 | 0.69 | SIGMAR1 (0.43) | SIGMAR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464834-A | Antidepressants, central nervous system | ADIR ET COMPAGNIE (FR) | 1995-11-07 | — | — | US | disclosed |