Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058469 | 1.00 | HTR1A (0.51) | HTR1ASIGMAR1TRPV1MEN1KMT2A | |
| SCHEMBL9145271 | 0.81 | HDAC1 (0.56) | HTR1ATRPV1MEN1KMT2AHDAC1 | |
| SCHEMBL9144249 | 0.78 | HTR5A (0.51) | HDAC6 | |
| SCHEMBL9144256 | 0.78 | HTR5A (0.51) | HDAC6 | |
| SCHEMBL22549325 | 0.77 | HTR1A (0.62) | HTR1ASIGMAR1MEN1KMT2AKDM4E | |
| SCHEMBL10614344 | 0.74 | SIGMAR1 (0.60) | HTR1ASIGMAR1 | |
| SCHEMBL24405173 | 0.74 | HTR1A (0.58) | HTR1ASIGMAR1MEN1KMT2AKDM4E | |
| SCHEMBL6369610 | 0.74 | HTR1A (0.71) | HTR1ASIGMAR1MEN1KMT2AKDM4E | |
| SCHEMBL17517486 | 0.73 | SIGMAR1 (0.68) | HTR1ASIGMAR1MEN1KMT2AKDM4E | |
| SCHEMBL1415530 | 0.71 | HTR1A (0.81) | HTR1ASIGMAR1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439915-A | Anxiolytic agents, antidepressants; for central nervous system disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-08-08 | — | — | US | disclosed |