SCHEMBL914604

SCHEMBL914604

CCOP(=O)(O)Cc1ccc(Sc2ccc(OC(C)O)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.37
LMNA P02545 2/20 0.37
THRB P10828 1/20 0.37
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
POLB P06746 2/20 0.33
CYP2C19 P33261 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
MMP12 P39900 1/20 0.33
HDAC1 Q13547 1/20 0.32
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
PPARD Q03181 1/20 0.32
KCNH2 Q12809 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL915293 0.88 SMN1; SMN2 (0.36) SMN1; SMN2LMNATHRBGAAHPGD
SCHEMBL915695 0.88 PTPN1 (0.37) SMN1; SMN2POLBCYP2C19HDAC1PGK1
SCHEMBL916355 0.88 POLB (0.36) SMN1; SMN2POLBCYP2C19HDAC1PGK1
SCHEMBL915281 0.88 PTPN5 (0.40) SMN1; SMN2GAAPOLBCYP2C19MMP2
SCHEMBL914969 0.86 PGK1 (0.45) SMN1; SMN2LMNATHRBGAAHPGD
SCHEMBL914843 0.84 HDAC1 (0.39) SMN1; SMN2GAAHPGDNPSR1POLB
SCHEMBL915507 0.83 NR1H4 (0.38) SMN1; SMN2GAAPOLBCYP2C19HDAC1
SCHEMBL915528 0.83 ALDH1A1 (0.38) SMN1; SMN2LMNAGAANPSR1POLB
SCHEMBL4439215 0.81 SMN1; SMN2 (0.39) SMN1; SMN2LMNATHRBGAAHPGD
SCHEMBL915868 0.80 NR1H2 (0.44) LMNAPOLBMMP2MMP9MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868126-B2 Process for producing polyester, polyester produced using said process, and polyester molded product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2011-01-11 US disclosed
EP-1842868-B1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT TOYO BOSEKI (JP) 2010-11-10 EP disclosed
US-20090082529-A1 Polyester, Process for Producing Polyester, and Polyester Molded Article TOYO BOSEKI KABUSHIKI KAISHA (JP) 2009-03-26 US disclosed
US-20080249280-A1 Process for Producing Polyester, Polyester Produced Using Said Process, and Polyester Molded Product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2008-10-09 US disclosed
EP-1932867-A1 POLYESTER, PROCESS FOR PRODUCTION OF POLYESTER, AND POLYESTER MOLDED ARTICLE Toyo Boseki Kabushiki Kasisha (JP) 2008-06-18 EP disclosed
EP-1842868-A1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT Toyo Boseki Kabushiki Kasisha (JP) 2007-10-10 EP disclosed