SCHEMBL914969

SCHEMBL914969

CC(O)Oc1ccc(Sc2ccc(CP(=O)(O)O)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 4/20 0.45
PGK2 P07205 4/20 0.45
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP12 P39900 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
LMNA P02545 2/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ENPP2 Q13822 1/20 0.39
THRB P10828 5/20 0.37
THRA P10827 4/20 0.37
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL915288 0.87 MMP2 (0.43) PGK1PGK2MMP2MMP9MMP12
SCHEMBL915317 0.86 PGK1 (0.49) PGK1PGK2ENPP2THRBTHRA
SCHEMBL916702 0.86 PGK1 (0.49) PGK1PGK2MMP2ENPP2THRB
SCHEMBL916007 0.86 PGK1 (0.49) PGK1PGK2MMP2MMP9GAA
SCHEMBL914604 0.86 SMN1; SMN2 (0.37) PGK1PGK2MMP2MMP9MMP12
SCHEMBL915134 0.82 PGK1 (0.45) PGK1PGK2SMN1; SMN2ENPP2THRB
SCHEMBL915128 0.81 PGK1 (0.45) PGK1PGK2ENPP2THRBTHRA
SCHEMBL914794 0.81 PGK1 (0.44) PGK1PGK2MMP2MMP9MMP12
SCHEMBL890769 0.80 LMNA (0.42) SMN1; SMN2LMNAGAAHPGDNPSR1
SCHEMBL20831585 0.79 POLB (0.56) PGK1PGK2MMP2MMP9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868126-B2 Process for producing polyester, polyester produced using said process, and polyester molded product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2011-01-11 US disclosed
EP-1842868-B1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT TOYO BOSEKI (JP) 2010-11-10 EP disclosed
US-20080249280-A1 Process for Producing Polyester, Polyester Produced Using Said Process, and Polyester Molded Product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2008-10-09 US disclosed
EP-1842868-A1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT Toyo Boseki Kabushiki Kasisha (JP) 2007-10-10 EP disclosed