Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP4 | P49662 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP9 | P55211 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845576 | 0.91 | AKR1B1 (0.37) | CASP6POLBAPEX1CTDSP1TDP1 | |
| SCHEMBL756044 | 0.75 | NR3C2 (0.60) | POLBTDP1LMNANR3C2ALDH1A1 | |
| SCHEMBL4268382 | 0.75 | MAPT (0.43) | CASP6POLBAPEX1CTDSP1TDP1 | |
| SCHEMBL2268117 | 0.73 | NR3C2 (0.44) | LMNANR3C2ALDH1A1KMT2AMAPT | |
| SCHEMBL27414020 | 0.73 | MAPT (0.42) | CASP6POLBLMNAALDH1A1KMT2A | |
| SCHEMBL9146981 | 0.72 | L3MBTL1 (0.45) | CASP6POLBLMNANR3C2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9143208 | 0.71 | L3MBTL1 (0.44) | CASP6POLBLMNANR3C2ALDH1A1 | |
| SCHEMBL758128 | 0.70 | ALDH1A1 (0.36) | CASP6TDP1MALT1LMNANR3C2 | |
| SCHEMBL5140408 | 0.70 | NR3C2 (0.41) | TDP1LMNANR3C2ALDH1A1KMT2A | |
| SCHEMBL9143544 | 0.67 | AKR1B1 (0.42) | CASP6TDP1MALT1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420126-A | Potassium channel activators | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0432893-A2 | Benzoxazine derivatives, their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |