Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ESPL1 | Q14674 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9147151 | 0.91 | CASP6 (0.38) | AKR1B1MALT1CASP6POLBAPEX1 | |
| SCHEMBL9145488 | 0.82 | BACE1 (0.38) | MALT1TDP1ALDH1A1NPC1RAB9A | |
| SCHEMBL9146937 | 0.80 | ABCC9 (0.36) | MALT1LMNAKDM4E | |
| SCHEMBL4268382 | 0.77 | MAPT (0.43) | CASP6POLBAPEX1CTDSP1TDP1 | |
| SCHEMBL9143544 | 0.74 | AKR1B1 (0.42) | AKR1B1MALT1CASP6TDP1ALDH1A1 | |
| SCHEMBL9143665 | 0.74 | AKR1B1 (0.43) | AKR1B1MALT1CASP6POLBAPEX1 | |
| SCHEMBL4260665 | 0.73 | L3MBTL1 (0.46) | AKR1B1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9725698 | 0.73 | MAPT (0.42) | AKR1B1CASP6POLBALDH1A1NPC1 | |
| SCHEMBL9145462 | 0.72 | POLB (0.41) | AKR1B1MALT1CASP6POLBAPEX1 | |
| SCHEMBL9147214 | 0.71 | POLB (0.41) | AKR1B1MALT1CASP6POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432893-A2 | Benzoxazine derivatives, their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |