SCHEMBL9147991

SCHEMBL9147991

O=C(Nc1ccc2nc(S)[nH]c2c1)Oc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.52
ALDH1A1 P00352 6/20 0.49
MAPT P10636 4/20 0.49
KDM4E B2RXH2 2/20 0.49
GRIN1 Q05586 1/20 0.47
GRIN2B Q13224 1/20 0.47
CYP1A2 P05177 1/20 0.47
RAD51 Q06609 2/20 0.47
POLB P06746 1/20 0.46
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
THRB P10828 1/20 0.45
GFER P55789 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HSD17B10 Q99714 1/20 0.45
KDR P35968 2/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.44
GAA P10253 1/20 0.44
TEK Q02763 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9147984 0.90 BRD4 (0.55) BRD4ALDH1A1MAPTKDM4ECYP1A2
SCHEMBL21017273 0.84 BAZ1A (0.60) ALDH1A1MAPTKDM4EPOLBKMT2A
SCHEMBL4576194 0.79 BAZ1A (0.49) ALDH1A1MAPTKDM4EPOLBKMT2A
SCHEMBL7485781 0.79 TP53 (0.48) ALDH1A1MAPTKDM4EPOLBKMT2A
SCHEMBL6152812 0.78 ALDH1A1 (0.55) ALDH1A1MAPTKDM4ECYP1A2POLB
SCHEMBL6608685 0.77 KDM4E (0.61) ALDH1A1MAPTKDM4EGRIN1GRIN2B
SCHEMBL13411810 0.77 ALDH1A1 (0.51) BRD4ALDH1A1MAPTKDM4ECYP1A2
SCHEMBL14344745 0.76 RAB9A (0.54) MAPTPOLBKMT2AMEN1THRB
SCHEMBL9153898 0.75 ALDH1A1 (0.53) BRD4ALDH1A1MAPTKDM4ECYP1A2
SCHEMBL13922193 0.74 FABP4 (0.49) ALDH1A1MAPTKDM4EPOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0249239-B1 Process for the formation of direct positive images FUJI PHOTO FILM CO LTD (JP) 1995-01-25 EP disclosed
EP-0283041-B1 DIRECT POSITIVE SILVER HALIDE PHOTOSENSITIVE MATERIAL AND METHOD FOR FORMING DIRECT POSITIVE IMAGE FUJI PHOTO FILM CO., LTD. (JP) 1992-10-07 EP disclosed
US-4954427-A Development of light-sensitive material in the presence of a nucleating agent and a nuceation accelerator FUJI PHOTO FILM CO., LTD. (JP) 1990-09-04 US disclosed
US-4952483-A NOVEL HYDRAZINE NUCLEATING AGENTS AND ACCELERATORS FUJI PHOTO FILM CO., LTD. (JP) 1990-08-28 US disclosed
US-4933265-A NUCLEATION PROMOTER FUJI PHOTO FILM CO., LTD. (JP) 1990-06-12 US disclosed
US-4886738-A COLOR REVERSAL MATERIAL WITH IMPROVED PUSH DEVELOPABILITY FUJI PHOTO FILM CO., LTD. (JP) 1989-12-12 US disclosed
EP-0283041-A1 Direct positive silver halide photosensitive material and method for forming direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1988-09-21 EP disclosed
EP-0249239-A2 Process for the formation of direct positive images FUJI PHOTO FILM CO., LTD. (JP) 1987-12-16 EP disclosed