Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | GRK5 | P34947 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | PRKX | P51817 | 1/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9147162 | 0.98 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1AURKADAPK3PRKD3 | |
| SCHEMBL8312415 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1LMNAMAPTCA1 | |
| SCHEMBL8688647 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1AURKADAPK3PRKD3 | |
| SCHEMBL8334566 | 0.83 | TLR8 (0.36) | SMN1; SMN2ALDH1A1LMNAMAPTCA1 | |
| SCHEMBL8329490 | 0.79 | TLR8 (0.40) | SMN1; SMN2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL8331898 | 0.79 | KDR (0.36) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8310400 | 0.79 | MAPT (0.36) | SMN1; SMN2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL9145807 | 0.78 | MAPT (0.40) | SMN1; SMN2ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL8333788 | 0.77 | SMN1; SMN2 (0.32) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8312356 | 0.76 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424443-A | Substituted benzothiazole derivatives, their preparation and use as herbicides | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |
| EP-0583353-A1 | SUBSTITUTED BENZOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND USE AS HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-02-23 | — | — | EP | disclosed |
| WO-1992020675-A1 | SUBSTITUTED BENZOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND USE AS HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-11-26 | — | — | WO | disclosed |