Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148367 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1LMNAKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL9147162 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL8334566 | 0.81 | TLR8 (0.36) | SMN1; SMN2ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL8329490 | 0.78 | TLR8 (0.40) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8310400 | 0.78 | MAPT (0.36) | SMN1; SMN2ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL8331898 | 0.78 | KDR (0.36) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8333788 | 0.75 | SMN1; SMN2 (0.32) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8312356 | 0.74 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL8554380 | 0.73 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL8310374 | 0.73 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1LMNAMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958295-A1 | SUBSTITUTED 2-(2,4(1H,3H)-PYRIMIDINDION-3-YL) BENZTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998033796-A1 | SUBSTITUTED 2-(2,4(1H,3H)-PYRIMIDINDION-3-YL) BENZTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-06 | — | — | WO | disclosed |