Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152736 | 0.85 | CYP17A1 (0.39) | CYP17A1AAK1KIF11FFAR1MGLL | |
| SCHEMBL9149303 | 0.84 | MAPT (0.51) | AAK1CYP3A4FFAR1 | |
| SCHEMBL9150208 | 0.84 | KIF11 (0.47) | AAK1CYP3A4KIF11FFAR1NR1H4 | |
| SCHEMBL10349477 | 0.83 | XDH (0.41) | TLR8 | |
| SCHEMBL9148591 | 0.83 | ESR2 (0.41) | AAK1CYP3A4ERN1TLR8ESR2 | |
| SCHEMBL9144856 | 0.83 | PTPN11 (0.38) | CYP17A1KIF11MGLLESR2 | |
| SCHEMBL10349480 | 0.80 | XDH (0.54) | AAK1CYP3A4 | |
| SCHEMBL9152228 | 0.79 | RARB (0.46) | CYP3A4MGLL | |
| SCHEMBL9150117 | 0.79 | S1PR1 (0.41) | CYP17A1KIF11MGLLESR2 | |
| SCHEMBL6938802 | 0.77 | FFAR1 (0.50) | AAK1CYP3A4FFAR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397504-A | Liquid crystal | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0315701-B1 | BIPHENYL COMPOUND | KANTO KAGAKU (JP) | 1993-12-29 | — | — | EP | disclosed |
| EP-0315701-A1 | BIPHENYL COMPOUND | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1989-05-17 | — | — | EP | disclosed |