Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9149303 | 0.90 | MAPT (0.51) | AAK1CYP3A4MCHR1FFAR1MAPT | |
| SCHEMBL9149696 | 0.86 | KIF11 (0.44) | KIF11AAK1CYP3A4HSD17B1MCHR1 | |
| SCHEMBL9144904 | 0.85 | CYP3A4 (0.44) | AAK1CYP3A4ALDH1A1HIF1AHSD17B1 | |
| SCHEMBL9152800 | 0.84 | PTPN11 (0.45) | KIF11AAK1CYP3A4HSD17B1MCHR1 | |
| SCHEMBL9149072 | 0.84 | CYP17A1 (0.41) | KIF11AAK1CYP3A4FFAR1NR1H4 | |
| SCHEMBL13991465 | 0.82 | ALDH1A1 (0.45) | KIF11AAK1CYP3A4ALDH1A1HIF1A | |
| SCHEMBL9151344 | 0.81 | RAB9A (0.60) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL8973461 | 0.81 | RAB9A (0.60) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL9148876 | 0.81 | MAPT (0.47) | ALDH1A1MAPTLMNAMAPK1RAB9A | |
| SCHEMBL9149352 | 0.79 | LMNA (0.60) | KIF11ALDH1A1HSD17B1FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397504-A | Liquid crystal | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0315701-B1 | BIPHENYL COMPOUND | KANTO KAGAKU (JP) | 1993-12-29 | — | — | EP | disclosed |
| EP-0315701-A1 | BIPHENYL COMPOUND | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1989-05-17 | — | — | EP | disclosed |