Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 12/20 | 1.00 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | PDE5A | O76074 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150020 | 0.83 | LTB4R (0.71) | LTB4RLTB4R2 | |
| SCHEMBL9149520 | 0.82 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL7972701 | 0.82 | LTB4R (1.00) | LTB4RLTB4R2GPR17 | |
| SCHEMBL9484292 | 0.73 | LTB4R (0.57) | LTB4RLTB4R2 | |
| SCHEMBL9617084 | 0.72 | LTB4R (0.69) | LTB4R | |
| SCHEMBL11797746 | 0.70 | TTR (0.51) | LTB4R | |
| SCHEMBL10979140 | 0.70 | LTB4R (0.54) | LTB4RLTB4R2PPARGPPARDPDE5A | |
| SCHEMBL9216249 | 0.70 | CNR1 (0.66) | LTB4R | |
| Octanedioate SCHEMBL30999498 | 0.69 | ALDH1A1 (0.67) | LTB4RLTB4R2 | |
| Triphenylene SCHEMBL7588535 | 0.68 | KMT2A (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442748-B1 | Improvements in and relating to leukotriene antagonists | LILLY CO ELI (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0442748-A1 | Improvements in and relating to leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1991-08-21 | — | — | EP | disclosed |
| US-4996230-A | Antiallergens, antiinflammatory agent | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |