Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039855 | 0.79 | MEN1 (1.00) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL15828669 | 0.79 | MEN1 (0.60) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL3085553 | 0.77 | MAPT (0.62) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL6595610 | 0.77 | TSHR (0.41) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL6176327 | 0.76 | MAPT (0.65) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL3072829 | 0.76 | MAPT (0.60) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL9149685 | 0.74 | MAPT (0.58) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL7828455 | 0.72 | MAOA (0.60) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL4778868 | 0.72 | GPR35 (0.63) | MAPTMEN1KMT2AGAATDP1 | |
| SCHEMBL5311674 | 0.72 | GABRP (0.56) | MAPTMEN1KMT2AGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |