Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 7/20 | 0.39 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28018211 | 1.00 | CA2 (0.40) | CA2FDPSLAP3MMP2KDM4E | |
| Phosphoric Acid SCHEMBL4648159 | 0.96 | CA2 (0.43) | CA2FDPSLAP3MMP2KDM4E | |
| Phosphoric Acid SCHEMBL28379315 | 0.96 | CA2 (0.43) | CA2FDPSLAP3MMP2KDM4E | |
| Phosphoric Acid SCHEMBL11382517 | 0.96 | CA2 (0.43) | CA2FDPSLAP3MMP2KDM4E | |
| Phosphoric Acid SCHEMBL7533290 | 0.96 | — | — | |
| Phosphoric Acid SCHEMBL28288180 | 0.92 | — | — | |
| Phosphoric Acid SCHEMBL28969469 | 0.89 | FDPS (0.38) | CA2FDPSLAP3MMP2KDM4E | |
| Phosphoric Acid SCHEMBL27938812 | 0.89 | LAP3 (0.41) | CA2FDPSLAP3MMP2KDM4E | |
| Phosphoric Acid SCHEMBL28053838 | 0.89 | FDPS (0.43) | CA2FDPSLAP3MMP2KDM4E | |
| Phosphoric Acid SCHEMBL29005800 | 0.88 | CA2 (0.43) | CA2FDPSLAP3MMP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106635260-A | Antioxidative and anticorrosive chemical additive for volume type filtering in biomass engine oil purifying filter element and preparation method of antioxidative and anticorrosive chemical additive | 李旺达 | 2017-05-10 | — | — | CN | disclosed |
| US-5476681-A | Hydrophobic agent protects foam from reacting with environmental moisture | BASF CORPORATION (US) | 1995-12-19 | — | — | US | disclosed |
| US-5405885-A | Reacting aromatic polyisocyanate with polyol composition including water as blowing agent in presence of lubricating oil to prevent foam from reacting with environmental water | BASF CORPORATION (US) | 1995-04-11 | — | — | US | disclosed |