Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFSF11 | O14788 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | IDE | P14735 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR1F | P30939 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150550 | 0.87 | TNFSF11 (0.56) | TNFSF11CA2CA9PSEN1PSEN2 | |
| SCHEMBL9149099 | 0.81 | KMT2A (0.49) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9154069 | 0.78 | KMT2A (0.48) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9152137 | 0.78 | KMT2A (0.48) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9152716 | 0.75 | KMT2A (0.55) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9615051 | 0.74 | KMT2A (0.51) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9150381 | 0.72 | KMT2A (0.47) | MEN1KMT2AHTR6ALDH1A1HTR1A | |
| SCHEMBL9333981 | 0.72 | MEN1 (0.51) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9153167 | 0.72 | HTR6 (0.57) | HTR6IDEDRD2HTR1AHTR1D | |
| SCHEMBL22694071 | 0.71 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516849-B1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5283251-A | Testosterone 5a-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0516849-A1 | INDOLE DERIVATIVES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-12-09 | — | — | EP | disclosed |
| WO-1991013060-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-05 | — | — | WO | disclosed |