Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9151658 | 0.82 | PPARA (0.44) | FAAHKDM4E | |
| SCHEMBL9154517 | 0.81 | BAZ2B (0.51) | FAAHKMT2AMEN1GAA | |
| SCHEMBL14930356 | 0.81 | GABRP (0.44) | HPGDKDM4EKMT2AMEN1MAPT | |
| SCHEMBL9147935 | 0.81 | BAZ2B (0.51) | FAAHKMT2AMEN1GAA | |
| SCHEMBL9151583 | 0.81 | BAZ2B (0.51) | FAAHKMT2AMEN1GAA | |
| SCHEMBL9150866 | 0.81 | GPR84 (0.40) | FAAHHTTTHRBKDM4EMAPT | |
| SCHEMBL9285452 | 0.79 | BAZ2B (0.53) | KMT2AMEN1GAA | |
| SCHEMBL9151030 | 0.78 | THRA (0.38) | THRBPKM | |
| SCHEMBL9151907 | 0.76 | DNM1 (0.46) | CYP1A2THRBKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL9146272 | 0.75 | DNM1 (0.45) | CYP1A2THRBKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35096-E | Antilipemic, anticholesterol, arteriosclerosis | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-11-21 | — | — | US | disclosed |
| US-5082856-A | Hyperlipemia, arteriosclerosis | MITSUBISHI KASEI CORPORATION (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0347902-A2 | Pyrrolecarboxylic acid derivatives | Mitsubishi Chemical Corporation (JP) | 1989-12-27 | — | — | EP | disclosed |