Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860046 | 0.91 | KMT2A (0.46) | GAAPOLQKMT2AALDH1A1GLA | |
| SCHEMBL9153457 | 0.89 | RAB9A (0.42) | MAPTGAAPOLQKMT2AALDH1A1 | |
| SCHEMBL9153519 | 0.86 | SLC6A2 (0.41) | AGTR2KMT2AGPBAR1 | |
| SCHEMBL9156475 | 0.86 | DRD4 (0.48) | KDM4EHSD17B10POLQKMT2AALDH1A1 | |
| SCHEMBL9153579 | 0.85 | KMT2A (0.40) | POLQKMT2AALDH1A1GLATSHR | |
| SCHEMBL9155738 | 0.84 | LMNA (0.46) | MAPTTSHR | |
| SCHEMBL9154411 | 0.83 | GABRP (0.41) | MAPTALDH1A1GLATSHR | |
| SCHEMBL9154159 | 0.83 | GABRP (0.41) | AGTR2 | |
| SCHEMBL9158562 | 0.82 | GABRP (0.39) | AGTR2GAAPOLQKMT2AALDH1A1 | |
| SCHEMBL7506948 | 0.82 | POLQ (0.48) | MAPTKDM4EGAAHSD17B10POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |