Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLQ | O75417 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PPIB | P23284 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153457 | 0.94 | RAB9A (0.42) | KMT2AALDH1A1GLATSHRTP53 | |
| SCHEMBL9156475 | 0.91 | DRD4 (0.48) | KMT2AALDH1A1POLQMEN1SMN1; SMN2 | |
| SCHEMBL9152131 | 0.91 | MAPT (0.42) | KMT2AALDH1A1GLATSHRPOLQ | |
| SCHEMBL9155738 | 0.89 | LMNA (0.46) | TSHRTP53PPIB | |
| SCHEMBL9131869 | 0.87 | ALDH1A1 (0.42) | KMT2AALDH1A1TSHRPOLQMEN1 | |
| SCHEMBL9153519 | 0.86 | SLC6A2 (0.41) | KMT2AMEN1AOC3 | |
| SCHEMBL9152678 | 0.86 | HTR3E (0.48) | KMT2AALDH1A1TP53POLQSMN1; SMN2 | |
| SCHEMBL4294754 | 0.86 | KMT2A (0.54) | KMT2APOLQMEN1GAAPPIB | |
| SCHEMBL9134250 | 0.85 | KMT2A (0.46) | KMT2AALDH1A1TP53POLQMEN1 | |
| SCHEMBL9153579 | 0.85 | KMT2A (0.40) | KMT2AALDH1A1GLATSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663204-A | CHOLECYSTOKININ AND GASTRIN ANTAGONIST FOR APPETITE REGULATORS, GASTROINTESTINAL DISORDERS AND NERVOUS SYSTEM DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-09-02 | — | — | US | disclosed |
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |