SCHEMBL9152871

SCHEMBL9152871

COC(=O)N[C@@H](CCCl)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 14/20 0.41
TGFBR1 P36897 1/20 0.40
NAALAD2 Q9Y3Q0 4/20 0.39
RIMKLA Q8IXN7 1/20 0.39
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
ALOX15 P16050 1/20 0.35
NFKB1 P19838 1/20 0.35
PTGS2 P35354 1/20 0.35
THPO P40225 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 1/20 0.34
NOD1 Q9Y239 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9152878 1.00 FOLH1 (0.41) FOLH1TGFBR1NAALAD2RIMKLAKDM4E
SCHEMBL28606410 0.89 FOLH1 (0.40) FOLH1TGFBR1NAALAD2RIMKLANOD1
SCHEMBL28908151 0.84 TAS1R3 (0.35) FOLH1SMN1; SMN2ALDH1A1
SCHEMBL28908150 0.84 TAS1R3 (0.35) FOLH1SMN1; SMN2ALDH1A1
SCHEMBL29153242 0.83 ATM (0.39) FOLH1NAALAD2RIMKLASMN1; SMN2NOD1
SCHEMBL29153240 0.83 ATM (0.39) FOLH1NAALAD2RIMKLASMN1; SMN2NOD1
SCHEMBL30918332 0.82 CTSK (0.49)
SCHEMBL627951 0.82 TGFBR1 (0.46) FOLH1TGFBR1NAALAD2RIMKLAKDM4E
SCHEMBL387926 0.82 TGFBR1 (0.46) FOLH1TGFBR1NAALAD2RIMKLANOD1
SCHEMBL627952 0.82 TGFBR1 (0.46) FOLH1TGFBR1NAALAD2RIMKLAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903194-A Preparation method of glufosinate-ammonium precursor and glufosinate-ammonium salt 三峡大学 2024-04-19 CN claimed
CN-115448950-B Preparation method of L-glufosinate-ammonium intermediate 中国药科大学 2025-05-16 CN disclosed
CN-117903194-A Preparation method of glufosinate-ammonium precursor and glufosinate-ammonium salt 三峡大学 2024-04-19 CN disclosed
CN-117567323-A Preparation method of (S) -4-chloro-2- ((methoxycarbonyl) amino) ethyl butyrate 湖北泰盛化工有限公司 2024-02-20 CN disclosed
US-5442088-A Reacting optically active S-homoserine lactone with hydrogen chloride in the presence of an alcohol, and reacting the resulting halogen substituted compound with a phosphorus compound HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-15 US disclosed