Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28596493 | 0.82 | ATM (0.44) | ALDH1A1FAAHTSHRMAPT | |
| SCHEMBL14891482 | 0.77 | GAA (0.36) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2743750 | 0.74 | GAA (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1407300 | 0.74 | GAA (0.64) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL4412 | 0.74 | — | — | |
| SCHEMBL7264474 | 0.72 | GAA (0.61) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL28285089 | 0.72 | — | — | |
| Malonic Acid Diethyl Ester SCHEMBL1864301 | 0.72 | GAA (1.00) | GAAMGAMSIMGAM2ALDH1A1 | |
| Malonic Acid Diethyl Ester SCHEMBL8636 | 0.72 | GAA (1.00) | GAAMGAMSIMGAM2ALDH1A1 | |
| Malonic Acid Diethyl Ester SCHEMBL1331824 | 0.72 | GAA (1.00) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406002-A | Benzondole derivative and synthesis method thereof | 商洛学院 | 2024-07-30 | — | — | CN | claimed |
| CN-110734441-B | 3, 3' -pyrrolidine indole spiro-compound and preparation method and application thereof | 广州大学 | 2020-09-04 | — | — | CN | claimed |
| CN-107556212-B | Method for preparing 2-diazo-acetoacetic acid p-nitrobenzyl ester | 台州昌霖化工科技有限公司 | 2020-03-24 | — | — | CN | claimed |
| CN-110734441-A | 3, 3' -pyrrolidine indole spiro-compound and preparation method and application thereof | 广州大学 | 2020-01-31 | — | — | CN | claimed |
| US-20050124596-A1 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2005-06-09 | — | — | US | claimed |
| CN-118406002-A | Benzondole derivative and synthesis method thereof | 商洛学院 | 2024-07-30 | — | — | CN | disclosed |
| CN-115108957-B | Synthesis method of chiral 2-phenylpyrrolidine | 深圳博瑞医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-110105305-B | Transition metal catalyzed C-H activation/cyclization synthesis 1,2-benzothiazine derivative green synthesis method | 四川大学 | 2023-01-06 | — | — | CN | disclosed |
| CN-109053550-B | Synthesis method of benzindole derivative | 陕西科技大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-110734441-B | 3, 3' -pyrrolidine indole spiro-compound and preparation method and application thereof | 广州大学 | 2020-09-04 | — | — | CN | disclosed |
| CN-107556212-B | Method for preparing 2-diazo-acetoacetic acid p-nitrobenzyl ester | 台州昌霖化工科技有限公司 | 2020-03-24 | — | — | CN | disclosed |
| CN-110734441-A | 3, 3' -pyrrolidine indole spiro-compound and preparation method and application thereof | 广州大学 | 2020-01-31 | — | — | CN | disclosed |
| US-20050124596-A1 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2005-06-09 | — | — | US | disclosed |
| US-20030149043-A1 | N-[(substituted five-membered di-or triaza diunsaturated ring)carbonyl] guanidine derivatives for the treatment of ischemia | PFIZER INC. | 2003-08-07 | — | — | US | disclosed |
| US-6492401-B1 | SODIUM HYDROGEN EXCHANGER TYPE 1 INHIBITORS; REDUCING PERIOPERATIVE MYOCARDIAL TISSUE DAMAGE | PFIZER, INC. | 2002-12-10 | — | — | US | disclosed |
| EP-1114045-A1 | 2-METHOXYIMINO-2-(PYRIDINYLOXYMETHYL)PHENYL ACETAMIDES WITH 5 MEMBERED HETEROCYCLIC RINGS ON THE PYRIDINE RING AS FUNGICIDES | Dow AgroSciences LLC (US) | 2001-07-11 | — | — | EP | disclosed |
| US-6133294-A | APPLYING AS FUNGICIDES | DOW AGROSCIENCES LLC | 2000-10-17 | — | — | US | disclosed |
| WO-2000015637-A1 | 2-METHOXYIMINO -2-(PYRIDINYLOXYMETHYL) PHENYL ACETAMIDES WITH 5 MEMBERED HETEROCYCLIC RINGS ON THE PYRIDINE RING AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2000-03-23 | — | — | WO | disclosed |
| US-4683296-A | ANTIBIOTICS, SILATION | BRISTOL-MYERS COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| EP-0040408-A1 | Beta-lactam compounds and process for production thereof | SANRAKU-OCEAN CO., LTD. (JP) | 1981-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149043-A1 | N-[(substituted five-membered di-or triaza diunsaturated ring)carbonyl] guanidine derivatives for the treatment of ischemia | NHERF1, SLC28A1, TNNI3 | GAA 794/4885MGAM 4141/4885SI 813/4885 |
| US-20050124596-A1 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | PPOX, PPIF, HMBS | GAA 2694/4885MGAM 817/4885SI 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.