SCHEMBL9155186

SCHEMBL9155186

Cc1ccc2c(CCO)cc(=O)[nH]c2c1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 4/20 0.45
HPGD P15428 3/20 0.45
GAA P10253 3/20 0.45
GLA P06280 2/20 0.45
MEN1 O00255 9/20 0.44
KMT2A Q03164 9/20 0.44
USP2 O75604 2/20 0.44
ALOX15 P16050 2/20 0.44
MAPT P10636 2/20 0.44
HSD17B10 Q99714 1/20 0.44
NCOA1 Q15788 1/20 0.44
NCOA3 Q9Y6Q9 1/20 0.44
LMNA P02545 1/20 0.42
MITF O75030 1/20 0.42
HTR2A P28223 1/20 0.42
POLB P06746 1/20 0.42
RAB9A P51151 1/20 0.42
PAX8 Q06710 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9152213 0.88 ALDH1A1 (0.48) ALDH1A1KDM4EHPGDGAAMEN1
SCHEMBL9153152 0.84 LMNA (0.42) ALDH1A1KDM4EHPGDGAAGLA
SCHEMBL12667294 0.83 MAPT (0.51) ALDH1A1KDM4EHPGDGAAGLA
SCHEMBL9160411 0.81 CHEK1 (0.49) ALDH1A1KDM4EHPGDGAAGLA
SCHEMBL1774421 0.81 FEN1 (0.45) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL9766051 0.79 ALDH1A1 (0.62) ALDH1A1KDM4EHPGDGAAMEN1
SCHEMBL8109985 0.78 KDM4E (0.59) ALDH1A1KDM4EHPGDGAAGLA
SCHEMBL9159365 0.77 KDM4E (0.49) ALDH1A1KDM4EHPGDGAAGLA
SCHEMBL9157239 0.76 GPR17 (0.47) ALDH1A1KDM4EHPGDGAAGLA
SCHEMBL2795205 0.76 KDM4E (0.67) ALDH1A1KDM4EHPGDGAAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5457099-A Carbostyril derivatives and antiallergic agent SAWAI PHARMACEUTICAL CO., LTD. (JP) 1995-10-10 US disclosed
EP-0577325-A1 Carbostyril derivatives and antiallergic agent SAWAI PHARMACEUTICAL CO., LTD. (JP) 1994-01-05 EP disclosed