Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR1F | P30939 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | IDE | P14735 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150550 | 0.83 | TNFSF11 (0.56) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3033927 | 0.81 | HTR6 (0.71) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL351630 | 0.81 | HTR6 (0.57) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL27662543 | 0.78 | PPARG (0.54) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL352748 | 0.77 | HTR6 (0.65) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL351209 | 0.77 | RORC (0.56) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL9152646 | 0.76 | IDE (0.43) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL352330 | 0.76 | HTR6 (0.58) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL351426 | 0.76 | HTR6 (0.55) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL352179 | 0.76 | PPARG (0.66) | HTR6HTR1ADRD2HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516849-B1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5283251-A | Testosterone 5a-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| WO-1991013060-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-05 | — | — | WO | disclosed |
| CN-1054250-A | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-09-04 | — | — | CN | disclosed |