Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155669 | 0.94 | CASR (0.48) | KMT2AMEN1MAPK1NPC1RAB9A | |
| SCHEMBL9156251 | 0.93 | L3MBTL1 (0.47) | KMT2AMEN1TSHRALDH1A1PPIB | |
| SCHEMBL9159917 | 0.92 | ROCK2 (0.45) | KMT2AMEN1TSHRPPIB | |
| SCHEMBL9157054 | 0.92 | CASR (0.42) | KMT2AMEN1TSHRMAPTALDH1A1 | |
| SCHEMBL9157342 | 0.91 | KMT2A (0.42) | KMT2AMEN1TSHRMAPTALDH1A1 | |
| SCHEMBL9157333 | 0.91 | KMT2A (0.42) | KMT2AMEN1TSHRMAPTALDH1A1 | |
| SCHEMBL9157339 | 0.91 | KMT2A (0.42) | KMT2AMEN1TSHRMAPTALDH1A1 | |
| SCHEMBL9152359 | 0.89 | CASR (0.44) | KMT2AMEN1TSHRMAPTALDH1A1 | |
| SCHEMBL9159354 | 0.89 | MAPT (0.52) | KMT2AMEN1TSHRMAPTALDH1A1 | |
| SCHEMBL9154458 | 0.88 | KMT2A (0.40) | KMT2AMEN1TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |