Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | MITF | O75030 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
| ▸ | PPIB | P23284 | 1/20 | 0.42 |
| ▸ | CBS | P35520 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154016 | 0.94 | KMT2A (0.52) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9156251 | 0.93 | L3MBTL1 (0.47) | CASRKMT2AMEN1PPIB | |
| SCHEMBL9159917 | 0.92 | ROCK2 (0.45) | CASRKMT2AMEN1PPIB | |
| SCHEMBL9157054 | 0.92 | CASR (0.42) | CASRRAB9ANPC1MITFSMN1; SMN2 | |
| SCHEMBL9134216 | 0.91 | MEN1 (0.43) | CASRRAB9ANPC1MITFSMN1; SMN2 | |
| SCHEMBL9134932 | 0.90 | RAB9A (0.55) | CASRRAB9ANPC1MITFSMN1; SMN2 | |
| SCHEMBL9157277 | 0.89 | CASR (0.43) | CASRRAB9ANPC1MITFSMN1; SMN2 | |
| SCHEMBL9152359 | 0.89 | CASR (0.44) | CASRRAB9ANPC1MITFSMN1; SMN2 | |
| SCHEMBL9157333 | 0.89 | KMT2A (0.42) | CASRRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9159354 | 0.89 | MAPT (0.52) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |