Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | PPIB | P23284 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154462 | 1.00 | KMT2A (0.40) | KMT2AMEN1CASRTSHRPPIB | |
| SCHEMBL9154453 | 1.00 | KMT2A (0.40) | KMT2AMEN1CASRTSHRPPIB | |
| SCHEMBL9157339 | 0.90 | KMT2A (0.42) | KMT2AMEN1CASRTSHRPPIB | |
| SCHEMBL9157342 | 0.90 | KMT2A (0.42) | KMT2AMEN1CASRTSHRPPIB | |
| SCHEMBL9157333 | 0.90 | KMT2A (0.42) | KMT2AMEN1CASRTSHRPPIB | |
| SCHEMBL9154016 | 0.88 | KMT2A (0.52) | KMT2AMEN1TSHRPPIBMAPT | |
| SCHEMBL9155669 | 0.86 | CASR (0.48) | KMT2AMEN1CASRPPIBMAPK1 | |
| SCHEMBL9152359 | 0.86 | CASR (0.44) | KMT2AMEN1CASRTSHRPPIB | |
| SCHEMBL9156251 | 0.85 | L3MBTL1 (0.47) | KMT2AMEN1CASRTSHRPPIB | |
| SCHEMBL9159917 | 0.84 | ROCK2 (0.45) | KMT2AMEN1CASRTSHRPPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |